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目的探讨早期乳腺癌保乳治疗的临床疗效和适应证,以提高乳腺癌的治疗水平。方法采用保乳手术治疗的30例早期乳腺癌患者(保乳组),同期年龄、病程等匹配的30例采取传统改良根治术治疗的乳腺癌患者(对照组),对2组患者的临床资料进行分析、比较。结果手术时间[(136.3±17.1)vs(181.7±16.5)min,P﹤0.05]、术中出血量[(300.5±19.8)vs(387.5±26.3)ml,P﹤0.05]保乳组均低于改良根治组;保乳组并发症发生率较改良根治组有所降低,但差异无统计学意义(10.0%vs30.0%,P﹥0.05)。术后1、3年复发率及生存率2组比较差异均无统计学意义(P均﹥0.05)。结论早期乳腺癌采用保乳治疗,手术损伤小,并发症较少,术后患侧乳房外形满意。保乳治疗是早期乳腺癌治疗的发展趋势。
Objective To investigate the clinical efficacy and indications of breast-conserving treatment for early breast cancer in order to improve the therapeutic level of breast cancer. Methods Thirty patients with breast cancer who underwent breast conserving surgery (breast-conserving group), the same age and course of disease were treated with modified radical mastectomy (control group). The clinical data of two groups Analysis, comparison. Results The operative time [(136.3 ± 17.1) vs (181.7 ± 16.5) min, P <0.05] and the amount of intraoperative blood loss [(300.5 ± 19.8 vs 387.5 ± 26.3) ml, P <0.05] Modified radical cure group; The incidence of complications in breastfeeding group was lower than that of modified radical cure group, but the difference was not statistically significant (10.0% vs 30.0%, P> 0.05). There was no significant difference in recurrence rate and survival rate between the two groups after 1 and 3 years (all P> 0.05). Conclusion breast conserving treatment of early breast cancer, less surgical injury, fewer complications, postoperative ipsilateral breast shape satisfactory. Breastfeeding treatment is the development trend of early breast cancer treatment.