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目的探讨心得安对抗精神病药物引起的静坐不能的疗效。资料和方法双盲对照研究。安坦(48例)和心得安(42例)治疗抗精神病药物引起的静坐不能。两组病人均选用椎体外系副反应量表和副反应量表(TESS)进行疗效评定。结果安坦组静坐不能均分由治疗前的3.24±0.43降至治疗后的0.84±1.26(P<0.01);心得安组静坐不能均分由治疗前的3.42±0.56降至治疗后的0.79±1.32(P<0.01)。两组植物神经系统副反应分值治疗前是3.13±2.59和3.05±2.48(P>0.05)。治疗后是6.58±2.54和3.54±2.42(P<0.01)。结论两种药物对抗精神病药物引起的静坐不能疗效近似;在对抗精神病药物引起的植物神经系统副反应的影响方面,心得安明显优于安坦。
Objective To investigate the efficacy of propranolol against psychosis caused by meddling. Materials and Methods Double-blind controlled study. Antan (48 cases) and propranolol (42 cases) treatment of antipsychotics cause sit-ins can not. Two groups of patients were selected vertebral extracorporeal side effects scale and side effects scale (TESS) for efficacy evaluation. Results Antan group could not be divided equally from 3.24 ± 0.43 before treatment to 0.84 ± 1.26 after treatment (P <0.01) 3.42 ± 0.56 to 0.79 ± 1.32 after treatment (P <0.01). The scores of adverse reactions in the autonomic nervous system were 3.13 ± 2.59 and 3.05 ± 2.48 before treatment (P> 0.05). After treatment were 6.58 ± 2.54 and 3.54 ± 2.42 (P <0.01). Conclusions Both medications can not induce similar effects due to medications caused by psychotropic drugs. Adamson is obviously superior to antan in counteracting the adverse effects of psychotropic drugs on the autonomic nervous system.