Oncomelania is the middle-parasitizeder of schistosome. The diffusion of Oncomelania with current will lead to the spread of schistosomiasis. River mechanics has been used in this paper. A systematic research with model test is engaged separately on Oncomelania hydrodynamic property. its sensitivity to water depth and velocity. Through this systematic experiment, a new thchnique of intake water without Oncomelania has been discovered. The technique can be widely applied to irrigation engineering. Oncomelania is the middle-parasitizeder of schistosome. The diffusion of Oncomelania with current will lead to the spread of schistosomiasis. River mechanics has been used in this paper. A systematic research with model test is engaged separately on Oncomelania hydrodynamic property. Its sensitivity to water Through this systematic experiment, a new thchnique of intake water without Oncomelania has been discovered. The technique can be widely applied to irrigation engineering.