目的 :了解严重急性呼吸综合征 (severe acute respiratory syndrom e,SARS)发病过程中合并心脏和肝脏损害的情况。 方法 :对我院近期收治的 6 9例 SARS患者病程中出现的与心脏、肝脏功能有关的临床表现、心电图及实验室检查结果进行分析。 结果 :6 9例患者中有 4 8例 (6 9.5 7% )出现心脏损害 ,4 2例 (6 0 .87% )出现肝脏损害 ,多数症状较轻 ;生化检查表现为心肌酶谱及肝功能指标异常 ;大部分患者有心电图改变 ,以窦性心动过速为主 ,部分有房性期前收缩和 ST- T变化。经一般治疗预后较好。死亡 7例 ,均死于呼吸衰竭或多器官功能衰竭 ;其中 1例尸检 ,光镜及电镜下均见肝脏和心脏的病理损害表现。结论 :SARS病程中合并心脏、肝脏损害较多见 ,这种损伤可能主要是病原本身所致 ,缺氧及药物可进一步加剧损害 Objective: To understand the complications of heart and liver damage in the pathogenesis of severe acute respiratory syndrome (SARS). Methods: The clinical manifestations of heart and liver function, electrocardiogram (ECG) and laboratory test results in the course of 69 SARS patients recently admitted in our hospital were analyzed. RESULTS: Forty-eight (69.5%) of the 69 patients had heart damage, and 42 (60.78%) had liver damage, with most of the symptoms less severe. The biochemical tests showed myocardial enzymes and liver function Indicators abnormalities; most patients have ECG changes to sinus tachycardia, part of the atrial contraction and ST-T changes. After the general treatment of a better prognosis. Seven died, both died of respiratory failure or multiple organ failure. One of them died autopsy, light and electron microscopy showed liver and heart pathological damage. Conclusions: Heart and liver damage are more common in the course of SARS. The damage may be mainly caused by the pathogen itself. Hypoxia and drugs can further aggravate the damage