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本文分析慢粒急变38例(急粒变35例,红白血病变2例,急淋变1例),男34例,女4例。年龄最小13岁,最大66岁,其中20～40岁26例(68.4%)。慢粒确诊至急变时间最短26天,最长11年零7个月,三年内急变者22(57.9%)。急变后的表现有发热、贫血、骨关节痛、肝大、脾大、淋巴结大,胸骨压痛、乏力及消瘦等。化验:多数有中度以上贫血,白细胞升高及血小板降低,血象幼稚细胞多在5%以上,骨髓象幼稚细胞在20%以上。作者提
In this paper, 38 cases of acute abrupt changes (35 cases of acute granulocytes, erythroleukemia in 2 cases, acute lymphoblastic 1 case), 34 males and 4 females. The youngest 13 years old, maximum 66 years old, of which 20 to 40 years old in 26 cases (68.4%). CML was diagnosed up to the shortest of 26 days, with the longest duration of 11 years and 7 months and 22 (57.9%) within 3 years. After the rapid change of fever, anemia, bone and joint pain, liver, spleen, lymph nodes, chest tenderness, fatigue and weight loss. Laboratory tests: Most have moderate to severe anemia, leukocytosis and thrombocytopenia, more blood cells more than 5% of naive cells, bone marrow-like naive cells in more than 20%. Author mention