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目的探讨氟比洛芬复合丙泊酚静脉麻醉应用于人工流产术的麻醉效果及最佳剂量。方法年龄19～42岁接受人工流产术者100例,随机分为4组(n=25):氟比洛芬25mg复合丙泊酚组(氟25mg组)、氟比洛芬50mg复合丙泊酚组(氟50mg组)、氟比洛芬75mg复合丙泊酚组(氟75mg组)、氟比洛芬空白乳剂复合丙泊酚组(对照组)。各组分别于注射丙泊酚前5min注射氟比洛芬或氟比洛芬空白乳剂。结果4组间麻醉诱导时间、手术时间无显著差异(P>0.05)。氟比洛芬各组苏醒时间、丙泊酚用量、术后宫缩痛评分及丙泊酚注射痛评分均小于对照组,氟50mg组、氟75mg组麻醉效果优于对照组(P<0.05)。术中4组血压、心率变化无明显差异,氟50mg组和氟75mg组体动发生率分别为28%(7/25)和20%(5/25),低于对照组60%(15/25),差异显著(P<0.05)。结论氟比洛芬50mg、75mg复合丙泊酚静脉麻醉应用于人工流产术麻醉效果好,苏醒质量高。
Objective To investigate the anesthetic effects and optimal dosage of flurbiprofen combined with propofol intravenous anesthesia in induced abortion. Methods One hundred patients aged 19-42 years who underwent induced abortion were randomly divided into 4 groups (n = 25): flurbiprofen 25mg combined with propofol (fluoride 25mg group), flurbiprofen 50mg combined with propofol (50mg fluoride group), flurbiprofen 75mg composite propofol group (fluorine 75mg group), and flurbiprofen blank emulsion combined propofol group (control group). Each group was injected with flurbiprofen or flurbiprofen blank emulsion 5 min before injection of propofol. Results There was no significant difference in induction time and operation time between the 4 groups (P> 0.05). The anesthesia effects of flurbiprofen group were better than that of the control group (P0.05), while the recovery time, the propofol dosage, the postoperative uterine contractions pain score and the propofol injection pain scores were lower than those of the control group. . There were no significant differences in blood pressure and heart rate among the four groups during the operation. The rates of body movement were 28% (7/25) and 20% (5/25) respectively in the 50 mg fluoride and 75 mg fluoride groups, which were lower than 60% (15 / 25), the difference was significant (P <0.05). Conclusion The application of flurbiprofen 50mg, 75mg propofol intravenous anesthesia in artificial abortion anesthesia is good, high quality of recovery.