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目的:探讨苗族和布依族女性血清神经内分泌激素水平,并比较影响两民族神经内分泌激素水平差异的因素。方法:2011年3月～2012年6月在贵州省黔南州中医医院治未病中心进行健康体检女性人群共359例,按民族将其分为苗族组(173例)和布依族组(186例)。采用化学发光免疫法测定两组研究对象血清中催乳素(PRL)、促黄体生成素(LH)、睾酮(TST)、尿促卵泡素(TSH)及多巴胺(DA)水平。结果:苗族组女性血清TST水平明显高于布依族组,而LH、TSH及DA水平则低于布依族组,差异有统计学意义(P<0.05)。根据年龄将两民族女性分为4个年龄段,两组20～29岁、30～39岁、40～49岁、50～59岁年龄段女性LH、TST、TSH及DA水平比较差异有统计学意义(P<0.05);两组20～29岁和30～39岁年龄段女性PRL水平比较差异无统计学意义(P﹥0.05);两组40～49岁和50～59岁年龄段女性PRL水平比较差异有统计学意义(P<0.05)。结论:苗族女性血清神经内分泌激素水平与布依族女性存在民族差异。
Objective: To explore the levels of serum neuroendocrine hormone in Miao and Buyi women and to compare the factors affecting the differences in neuroendocrine hormones between the two ethnic groups. Methods: From March 2011 to June 2012, 359 female subjects were enrolled in the health center of Guizhou Qiannan State Hospital of Traditional Chinese Medicine. According to the ethnic groups, they were divided into Miao group (173 cases) and Buyi group (186 cases) example). The level of serum prolactin (LH), testosterone (TST), follicle stimulating hormone (TSH) and dopamine (DA) were measured by chemiluminescence immunoassay. Results: The TST level of Miao women was significantly higher than that of Buyi group, while the levels of LH, TSH and DA were lower than that of Buyi group (P <0.05). According to the age, the two nationality women were divided into four age groups. There were statistically significant differences in the levels of LH, TST, TSH and DA between the two groups of 20-29, 30-39, 40-49 and 50-59 years old (P <0.05). There was no significant difference in PRL levels between the two groups (20--29 years old and 30-39 years old) (P> 0.05). There were no significant differences in PRL between the two groups (40-49 years old and 50-59 years old) The difference was statistically significant (P <0.05). Conclusion: There are ethnic differences between Miao women ’s serum neuroendocrine hormone levels and Buyi women.