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对６０例冠心病患者与６０例健康人血脂及载脂蛋白Ａ１和Ｂ进行测定显示，冠心病患者血清Ｔｃｈ、ＨＤＬ与健康人无显著差异；ＴＧ、ＬＤＬ、ＡｐｏＢ、ＡｐｏＢ／ＡｐｏＡ－Ｉ比值均显著高于健康人（Ｐ＜０．０１）；ＡｐｏＡ－Ⅰ显著低于健康人（Ｐ＜０．０５）。血脂正常的冠心病患者ＡｐｏＢ、ＡＰＯＢ／ＡｐｏＡ－Ⅰ比值也显著高于健康人（Ｐ＜０．０１）；ＡｐｏＡ－Ⅰ也显著低于健康人（Ｐ＜０．０１）．表明检测载脂蛋白比血脂能更好地预测冠心病，ＡｐｏＢ／ＡｐｏＡ－Ⅰ比值是鉴别有无冠心病的最佳指标。
The serum levels of lipids and apolipoproteins A1 and B in 60 patients with coronary heart disease and 60 healthy people showed no significant difference in serum Tch and HDL between CHD, LDL, ApoB and ApoB / ApoA-I (P <0.01). ApoA-Ⅰ was significantly lower than that in healthy subjects (P <0.05). The ApoB and APOB / ApoA-Ⅰ ratios were also significantly higher in patients with normal blood lipids than those in healthy subjects (P <0.01). ApoA-Ⅰ was also significantly lower than that in healthy subjects (P <0.01). The results showed that detecting apolipoprotein could better predict coronary heart disease than blood lipid. The ratio of ApoB / ApoA-Ⅰ was the best indicator of coronary heart disease.