论文部分内容阅读
目的 :观察大总量脑脊液置换术治疗蛛网膜下腔出血的有效性及安全性。方法 :腰穿缓慢放出血性脑脊液 5～ 10 ml,以等量生理盐水进行置换 5～ 10轮 ,每次置换出脑脊液总量为 4 0～ 10 0 ml,总疗程为 3～ 7次。结果 :10 4例经脑脊液置换后头痛、呕吐、意识障碍迅速缓解 ,脑血管痉挛、脑积水等并发症明显减少 ,明显优于对照组 (P <0 .0 1或 P <0 .0 5 )。结论 :应用大总量脑脊液置换术治疗蛛网膜下腔出血是一种迅速缓解头痛、呕吐、意识障碍 ,减少脑血管痉挛、脑积水等并发症发生及降低病死率、致残率的有效方法。
Objective: To observe the effectiveness and safety of large total cerebrospinal fluid replacement in the treatment of subarachnoid hemorrhage. Methods: The lumbar puncture slowly release hemorrhagic cerebrospinal fluid (5 ~ 10 ml) and replace with normal saline for 5 ~ 10 rounds. The volume of cerebrospinal fluid was 40 ~ 100 ml, and the total course of treatment was 3 ~ 7 times. Results: The headache, vomiting and disturbance of consciousness were quickly relieved in 104 cases after CSF replacement. The complications such as cerebral vasospasm and hydrocephalus were significantly decreased, which were significantly better than those in the control group (P <0.01 or P <0.05) ). Conclusion: The treatment of subarachnoid hemorrhage with large total cerebrospinal fluid replacement is an effective method to relieve headache, vomiting, disturbance of consciousness, reduce the occurrence of cerebral vasospasm, hydrocephalus and other complications and reduce the mortality and disability rate .