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用ELISA法同时检测了86例脑血管病(CVD)患者血清脂蛋白(a)[LP(a)]及血浆氧化修饰低密度脂蛋白(OMLDL)浓度,对比分析了两者浓度曲线分布特点、不同CVD患者LP(a)及OMLDL浓度变化、两者高浓度时CVD患者的阳性率及危险度比数比。结果发现CVD患者检测OMLDL较LP(a)更敏感,提示OMLDL可能是较LP(a)更重要的CVD危险因素。
Serum lipoprotein (a) [LP (a)] and plasma oxidized low density lipoprotein (OMLDL) concentrations in 86 patients with cerebrovascular disease (CVD) were simultaneously detected by ELISA. The distribution characteristics of the two concentrations were compared and analyzed. LP (a) and OMLDL concentrations in different CVD patients, the positive rate and risk ratio of CVD patients at high concentrations of the two. The results showed that CVD patients were more sensitive to detect OMLDL than LP (a), suggesting that OMLDL may be a more important CVD risk factor than LP (a).