脉压的大小是反映动脉粥样硬化的一个指标,其较收缩压和舒张压更能反映大动脉僵硬度的变化,并与心室肥厚、冠心病、心律失常、脑卒中等心脑血管事件呈显著相关。近来研究显示脉压指数综合反映了血管的固有顺应性和动态顺应性,在评价血管硬化方面较脉压更有优越性。现对原发性高血压患者脉压和脉压指数与靶器官损害关系的研究进展作一综述。 The size of pulse pressure is an indicator of atherosclerosis, which reflects the change of aortic stiffness better than systolic and diastolic pressure. It is also significantly associated with cardiovascular and cerebrovascular events such as ventricular hypertrophy, coronary heart disease, arrhythmia and stroke Related. Recent studies have shown that the pulse pressure index reflects the inherent vascular compliance and dynamic compliance, evaluation of vascular sclerosis more superior than pulse pressure. The research progress of the relationship between pulse pressure and pulse pressure index and target organ damage in patients with essential hypertension is reviewed.