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目的 :研究盐酸坦索罗辛对高龄前列腺增生患者的疗效。方法 :对 30例 75岁以上症状性BPH给予盐酸坦索罗辛 0 .2mg口服 1次 /d ,治疗观察 3个月。结果 :患者主观症状明显改善 ,治疗后 1月及 3月国际前列腺症状评分 (IPSS)分别降低 19% ,31.8% ,最大尿流率 (MFR)分别提高 2 0 % ,35 .2 %。治疗 3月B超测定残余尿减少 42 .8%。盐酸坦索罗辛对脉搏、血压及前列腺体积无影响。结论 :盐酸坦索罗辛对高龄BPH患者安全、有效 ,它能使患者主观症状、客观体征和生活质量有明显改善 ,无明显严重副作用。
Objective: To study the efficacy of tamsulosin hydrochloride in elderly patients with benign prostatic hyperplasia. Methods: Thirty patients with symptomatic BPH over 75 years old were given tamsulosin hydrochloride 0.2 mg orally once daily for 3 months. Results: Subjective symptoms were significantly improved in patients with IPSS 19%, 31.8%, and maximum flow rate (MFR) increased by 20% and 35.2% at January and March after treatment, respectively. Treatment March B-measured residual urine decreased 42.8%. Tamsulosin hydrochloride has no effect on pulse, blood pressure and prostate volume. Conclusion: Tamsulosin hydrochloride is safe and effective for elderly patients with BPH. It can significantly improve subjective symptoms, objective signs and quality of life of patients with no serious side effects.