糖尿病学近年来进展显著,特别是在糖尿病治疗方面取得的成绩尤其引人瞩目。在诸多领域(例如人胰岛素、持续胰岛素皮下注射疗法、糖尿病知识普及等),相继发表过许多新见解。现择其要者,简述如下。一、结构异常的胰岛素(芝加哥胰岛素) 很早以前就曾有人推测,是否存在由于胰岛素结构异常而表现为糖尿病状态的患者。这个推测被后来的一系列的报告所证实。首先是Steiner氏发现了胰岛素的前身——胰岛素原。不久Gabbay氏等报告了一个家族性高胰岛素原血症的家系。在这个家系的成员中,有 Diabetes has made significant progress in recent years, especially in the treatment of diabetes mellitus particularly impressive. In many areas (such as human insulin, sustained insulin subcutaneous injections, diabetes, knowledge popularization), have published many new insights. Now choose their best, briefly as follows. First, the structural abnormalities of insulin (Chicago Insulin) Long ago it was speculated that there are due to structural abnormalities in the insulin and diabetic patients showed. This speculation was confirmed by a series of later reports. The first is Steiner’s discovery of insulin’s predecessor, proinsulin. Soon Gabbay et al. Reported a pedigree of familial hyperinsulinism. Among the members of this pedigree, there is