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目的 :研究声门上喉癌中 nm23H1,表皮生长因子受体 (epidermal growth factor receptor,EGFR)表达及其与颈淋巴结转移和预后的关系。方法：回顾分析 77例声门上喉鳞癌和 23例癌旁正常喉粘膜标本。应用免疫组化技术研究 nm23H1,EGFR的表达。结果：声门上喉鳞癌中 nm23H1,EGFR的阳性表达率为 76.62％和 72.73％。声门上喉鳞癌和癌旁正常喉粘膜中 nm23H1和 EGFR表达具有显著差异（ P
Objective: To investigate the expression of nm23H1, epidermal growth factor receptor (EGFR) in supraglottic carcinoma and its relationship with cervical lymph node metastasis and prognosis. Methods: A retrospective analysis of 77 cases of supraglottic squamous cell carcinoma and 23 cases of adjacent normal laryngeal mucosa specimens. Immunohistochemistry was used to study the expression of nm23H1 and EGFR. Results: The positive rates of nm23H1 and EGFR in supraglottic squamous cell carcinoma were 76.62% and 72.73% respectively. There were significant differences in the expression of nm23H1 and EGFR in supraglottic squamous cell carcinoma and normal laryngeal mucosa (P