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目的:探讨旋磁场和尼莫地平对小鼠血清、脑组织、心组织和肝组织的一氧化氮(NO)含量的影响。方法: NO的测定用改良的Griess法。结果:曝磁给药组小鼠血清NO含量极低于对照组、曝磁组和给药组(P<0．01);给药组 小鼠血清NO含量极低于对照组(P<0．01);曝磁组小鼠脑组织和心组织NO含量极低于对照组(P<0．01);曝磁给药组 小鼠脑组织NO含量极高于曝磁组(P<0．01);曝磁给药组小鼠心组织NO含量极高于对照组、给药组和曝磁组(P< 0．01);曝磁给药组和曝磁组小鼠肝组织NO含量极高于对照组(P<0．01);曝磁给药组小鼠肝组织NO含量高于给药组 (P<0．05)。结论:旋磁场和尼莫地平对小鼠血清、脑组织、心组织和肝组织的NO含量有一定影响。
Objective: To investigate the effect of rotating magnetic field and nimodipine on the content of nitric oxide (NO) in serum, brain tissue, heart and liver of mice. Methods: The NO was determined using a modified Griess method. Results: The content of NO in the serum of the mice in the exposed group was significantly lower than that in the control group, the exposed group and the administered group (P <0.01) (P <0.01). The content of NO in brain tissue and heart tissue of the exposed group was significantly lower than that of the control group (P <0.01) .01). The content of NO in the heart tissue of the exposed group was significantly higher than that in the control group, the drug-treated group and the exposed group (P <0.01) (P <0.01). The content of NO in the liver tissue of the mice in the exposed group was higher than that in the control group (P <0.05). CONCLUSION: Rotary magnetic field and nimodipine exert some influence on NO content in serum, brain, heart and liver of mice.