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吸入性皮质激素(ICS)是目前最有效的抗哮喘药物。作者应用双重能量X线吸收测定法(DEXA)研究6个月二丙酸氯地米松(BDP)治疗对腰椎骨有机物含量的作用,探讨其损害哮喘儿童骨密度的潜在危险性。 患者和方法 确诊的门诊哮喘儿童35例,年龄5～14岁,其中30例完成全程治疗。根据哮喘的严重程度分为两组:①组(BDP组)14例,平均年龄9.1岁,均为中度哮喘。通过定量吸入器吸入BDP300～400μg/d(分2～3次吸入),至少6个月。②组(对照组)16例,平
Inhaled corticosteroids (ICS) is by far the most effective anti-asthma drug. The authors used double energy X-ray absorptiometry (DEXA) to study the effect of 6-month treatment with beclomethasone dipropionate (BDP) on the organic content of lumbar vertebrae, and to explore the potential risk of compromising bone mineral density in asthmatic children. Thirty-five outpatients with asthma were diagnosed by the patient and the method, aged 5 to 14 years, of whom 30 completed the full course of treatment. According to the severity of asthma divided into two groups: ① group (BDP group) 14 cases, mean age 9.1 years, were moderate asthma. By inhalation of metered-dose inhaler BDP 300 ~ 400μg / d (2 or 3 inhalations) for at least 6 months. ② group (control group) 16 cases, flat