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目的 探讨伊班膦酸钠 (艾本 )及其联合化疗对乳腺癌骨转移的疗效。方法 2 3例单用伊班膦酸钠治疗 ,2 5例伊班膦酸钠联合化疗。比较两种方法的疗效。结果 单用伊班膦酸钠治疗 ,疼痛缓解率87% (2 0 / 2 3例 ) ,卡氏评分标准平均提高 10分 ;伊班膦酸钠加化疗组 ,疼痛缓解率 10 0 % (2 5 / 2 5例 ) ,卡氏评分标准平均提高 2 0分。结论 单用伊班膦酸钠或伊班膦酸钠加化疗对乳腺癌骨转移的疗效均好 ,可缓解疼痛 ,促进骨质修复。伊班膦酸钠加化疗效果更佳。
Objective To investigate the effect of ibandronate (Aiben) and its combination chemotherapy on bone metastasis in breast cancer. Methods Twenty-three patients were treated with ibandronate alone and 25 patients received ibandronate combined with chemotherapy. Compare the efficacy of the two methods. The results were treated with ibandronate alone, the pain relief rate was 87% (20/23 cases), the Karnofsky score was improved by an average of 10 points, and the ibandronate plus chemotherapy group had a pain relief rate of 100% (2%). In 5/25 cases, the Karnofsky score increased by an average of 20 points. Conclusions The use of ibandronate or ibandronate plus chemotherapy for bone metastases in breast cancer is effective and can relieve pain and promote bone repair. Ibandronate plus chemotherapy is better.