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目的:通过分析不同年龄女性人群宫颈癌及癌前病变的血液检查和临床特征及治疗等情况,从而可更好地了解宫颈癌及癌前病变患者的临床特点及规律,为临床防治宫颈癌提供参考。方法:截取2012年5月-2014年8月期间82例宫颈癌及癌前病变患者的临床资料进行回顾性分析与总结,并按照患者年龄分组为治疗一组(≤45岁)与治疗二组(>45岁),各41例。结果:治疗二组患者主要表现为引道不规则流血,且以宫颈癌Ⅱ期为主,占56.1%(23/41);而治疗一组表现为接触性出血,主要以CINΙ~Ⅲ期、宫颈癌0~Ι期为主,分别占43.9%(18/41)、31.7%(13/41)。两组淋巴结转移和病理学类型及分级比较无统计学意义;治疗二组主要采用手术联合放、化疗综合治疗,且采用盆腔淋巴结清扫术、广泛子宫双附件切除人数较多;而治疗一组以单纯手术治疗为主,且大多保留卵巢功能。结论:正确了解及掌握不同年龄宫颈癌及癌前病变患者临床病理特点,从而可为患者临床诊断及预后判断提供重要价值。
OBJECTIVE: To analyze the clinical characteristics and treatment of cervical cancer and precancerous lesions in women of different ages so as to better understand the clinical features and rules of cervical cancer and precancerous lesions, and to provide clinical prevention and treatment of cervical cancer reference. Methods: The clinical data of 82 cases of cervical cancer and precancerous lesions collected from May 2012 to August 2014 were retrospectively analyzed and summarized. Patients in treatment group (≤45 years) and treatment group Ⅱ (> 45 years old), 41 cases each. Results: The treatment of the two groups of patients mainly manifested as irregular bleeding, and cervical cancer stage Ⅱ, accounting for 56.1% (23/41); and the treatment of a group of manifestations of contact bleeding, mainly CIN1 ~ Cervical cancer 0 ~ 1-based, accounting for 43.9% (18/41), 31.7% (13/41). Two groups of lymph node metastasis and pathological types and grading were not statistically significant; the treatment of the two groups were combined with radiotherapy and chemotherapy combined treatment, and the use of pelvic lymph node dissection, extensive uterine double attachment resection more; and treatment of a group of Surgical treatment alone, and most of them retain ovarian function. Conclusion: Correct understanding and mastery of clinicopathological characteristics of patients with cervical cancer and precancerous lesions of different ages can provide important value for clinical diagnosis and prognosis of patients.