在胆石成因研究中,已证实胆汁中存在一类与 ConA 凝集素特异性结合的可溶性糖蛋白,其中某些组份具有明显的促成核作用。但对不同病变的胆囊上皮细胞中能与 ConA 凝集素结合的膜糖蛋白量是否存在差异,未见报道。作者利用 ConA-HRP 定位技术观察了10组不同病变胆囊上皮细胞,结合图象分析处理,结果发现除胆囊胆固醇多发性结石组其上皮细胞中所含 ConA 受体高于对照组外(P<0.01),余均无统计学意义。 In the genesis of gallstone, it has been confirmed that there is a class of soluble glycoproteins in the bile that specifically bind to ConA-lectin, some of which have obvious nucleation-promoting effects. However, different lesions of gallbladder epithelial cells with ConA lectin binding membrane glycoprotein whether there is a difference, has not been reported. The authors used ConA-HRP localization technique to observe 10 groups of different pathological gallbladder epithelial cells, combined with image analysis and treatment, found that in addition to cholesterol gallstone gallstone group epithelial cells contained ConA receptor higher than the control group (P <0.01 ), I have no statistical significance.