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目的探讨人乳头瘤病毒(HPV)感染与宫颈病变的关系。方法 2007-02-2008-06在北京市垂杨柳医院就诊的患者为研究对象,对疑为HPV感染或宫颈病变的841病例进行HPV分型检测和液基细胞学检查,对细胞学诊断异常或HPV检测为阳性的病例进行阴道镜活检。结果 HPV检测阳性率为43.28%,液基细胞学诊断异常占45.30%。组织学诊断阳性≥CINI中HPV与细胞学检测阳性率均大于75%。结论 HPV分型检测联合液基细胞学和组织学更能有效地筛查宫颈病变细胞,为临床防治宫颈癌提供更可靠的科学依据。
Objective To investigate the relationship between human papillomavirus (HPV) infection and cervical lesions. Methods A total of 841 cases of suspected HPV infection or cervical lesion were examined by HPV genotyping and liquid-based cytology in patients who were treated in Chuihyangliu Hospital of Beijing from February 2007 to June 2007. The diagnosis of cytology was abnormal or Colposcopy biopsy was performed on cases with positive HPV testing. Results The positive rate of HPV test was 43.28% and the abnormality of liquid-based cytology was 45.30%. Histological diagnosis positive ≥ CINI HPV and cytology positive rates were greater than 75%. Conclusion HPV genotyping combined with liquid-based cytology and histology is more effective screening of cervical lesions of cells for the clinical prevention and treatment of cervical cancer provide a more reliable scientific basis.