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目的:探讨左卡尼汀治疗新生儿窒息致心肌损害的临床应用效果。方法:选取本院2013年4月-2015年2月收治的新生儿窒息致心肌损害患儿85例,按随机数字表法分为对照组42例、观察组43例,对照组患儿给予常规治疗,观察组在对照组治疗基础上给予左卡尼汀治疗,对比两组患儿临床治疗效果。结果:观察组患儿治疗总有效率为90.70%,高于对照组患儿的73.81%,,组间比较,差异具有统计学意义(P<0.05);两组患儿治疗前肌酸激酶同功酶(CK-MB)、天冬氨酸转氨酶(AST)、肌酸激酶(CK)、肌钙蛋白T(Tn T)对比,差异无统计学意义(P>0.05),治疗后观察组患儿CK-MB、AST、CK、Tn T改善情况优于对照组,差异具有统计学意义(P<0.05)。结论:左卡尼汀在治疗新生儿窒息致心肌损害中的应用效果显著。
Objective: To investigate the clinical effect of levocarnitine on neonatal asphyxia induced myocardial damage. Methods: Eighty-five children with myocardial damage caused by neonatal asphyxia were selected from April 2013 to February 2015 in our hospital. According to the random number table, 42 children in the control group and 43 in the observation group were enrolled. Children in the control group were given conventional The treatment group and the observation group were treated with levocarnitine on the basis of the control group, and the clinical effects were compared between the two groups. Results: The total effective rate of treatment group was 90.70%, higher than that of control group (73.81%), the difference was statistically significant (P <0.05). Before treatment, creatine kinase There was no significant difference in CK-MB, AST, creatine kinase (CK) and troponin T (Tn T) between the two groups The improvement of CK-MB, AST, CK, Tn T was better than that of the control group (P <0.05). Conclusion: L-carnitine is effective in treating myocardial damage caused by neonatal asphyxia.