骨肉瘤是骨的原发性恶性肿瘤 ,在原发性骨肿瘤中骨肉瘤的发病率仅次于浆细胞骨髓瘤居第 2位。目前 ,骨肉瘤的生存率已经有了明显提高 ,但有一类高度恶性的骨肉瘤 ,与肿瘤发现的早晚、治疗措施的应用无关 ,病人在短期内死亡 ,近期的研究认为这一类骨肉瘤可能属于高危骨肉瘤类[1] Osteosarcoma is a primary malignancy of bone, and the incidence of osteosarcoma is second only to plasma cell myeloma in primary bone tumors. At present, the survival rate of osteosarcoma has been significantly improved, but there is a class of highly malignant osteosarcoma, tumor discovery sooner or later, the application of treatment has nothing to do, the patient died in the short term, recent studies suggest that this type of osteosarcoma may Belongs to high-risk osteosarcoma [1]