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目的探讨硫酸镁联合川芎嗪治疗新生儿缺血缺氧性脑病的疗效。方法将100例HIE患儿随机分为治疗组和对照组,对照组采用三维持、三对症等综合治疗,治疗组在对照组的基础上加用硫酸镁联合川芎嗪治疗。结果治疗后3d,7d,10d两组HBNA评分比较,治疗组明显高于对照组(P<0.05);临床疗效比较,治疗组总有效率96%,对照组为68%,两者比较差异有统计学意义(P<0.05)。结论硫酸镁联合川芎嗪治疗新生儿缺血缺氧性脑病可明显改善患儿的临床症状,显著提高疗效。
Objective To investigate the curative effect of magnesium sulfate combined with ligustrazine on neonatal hypoxic-ischemic encephalopathy. Methods 100 HIE children were randomly divided into treatment group and control group. The control group was treated with three-dimensional and three-symptomatic treatment. The treatment group was treated with magnesium sulfate and ligustrazine on the basis of the control group. Results The HBNA scores of the two groups were significantly higher than those of the control group on the 3d, 7d and 10d after treatment (P <0.05). Compared with the control group, the total effective rate was 96% in the treatment group and 68% in the control group Statistical significance (P <0.05). Conclusion Magnesium sulfate and ligustrazine treatment of neonatal hypoxic-ischemic encephalopathy can significantly improve the clinical symptoms of children, significantly improve the efficacy.