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采用 Ｍ Ｔ Ｔ 比色法与双抗体夹心法对３８ 例食管癌患者进行了手术前后 Ｉ Ｌ－ ２ 与 Ｓ Ｉ Ｌ－２ Ｒ 水平检测， 并以正常人作对照。结果表明：食管癌患者手术前血清 Ｉ Ｌ－ ２ 活性明显低于正常人，血清 Ｓ Ｉ Ｌ－ ２ Ｒ 水平明显地高于正常人；术后６ 个月复发者 Ｉ Ｌ－ ２ 与 Ｓ Ｉ Ｌ－ ２ Ｒ 水平持续异常，未复发者 Ｉ Ｌ－ ２ 与 Ｓ Ｉ Ｌ－ ２ Ｒ 水平恢复正常。观察了患者免疫功能的变化与肿瘤的发生及预后密切相关。
MTT colorimetric and double-antibody sandwich assays were performed on 38 patients with esophageal cancer before and after surgery for I L-2 and S I L-2 R levels, and were compared with normal controls. The results showed that the activity of serum I L - 2 in patients with esophageal cancer before operation was significantly lower than that of normal people, and the serum level of S I L - 2 R was significantly higher than that of normal people; relapsed patients with I L - 2 and S I L at 6 months after operation. - 2 R levels remained abnormal, and the levels of I L- 2 and S I L- 2 R returned to normal without relapse. It was observed that changes in the patient’s immune function were closely related to the occurrence and prognosis of the tumor.