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引言药物中有很多种类屬于有机胺类化合物,如各种生物鹼等,它們按现在药典方法的含量测定手續是相当麻煩的,要經过多次抽提处理及洗滌等手續;所費的时間颇長,且誤差的可能性亦較多。非水溶液滴定是近几年来發展起来的分析方法,它利用溶剂的特性来改变溶質的酸鹼相对强度,把弱酸或弱鹼(水中)的物質改置在特殊的非水溶剂介質中,使其相对地变成强酸或强鹼来直接滴定,可以大大地簡化操作手續和节省时間。
Introduction There are many types of drugs belonging to organic amine compounds, such as various alkaloids, which according to the current Pharmacopoeia method of determination is quite troublesome, to go through several extraction processing and washing procedures; time Between the long, and the possibility of more errors. Non-aqueous titration is an analytical method developed in recent years. It uses the characteristics of solvents to change the relative acid-base strength of solutes. The weak acids or weak bases (water) are repositioned in special non-aqueous solvents to make them Relatively strong acid or alkali into a direct titration, can greatly simplify the procedures and save time.