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B细胞被抗原或抗Ig抗体等物质激活后增殖,并分化为大量分泌抗体的浆细胞。此乃体内抗体的唯一来源。足见B细胞在体液免疫应答中占有的重要位置。因此,B细胞的功能状态及其调节因素甚受医学界重视。B细胞的活化过程是一个受多种因素调节的连续而又复杂的过程,其中最重要的直接影响为T细胞和巨噬细胞产生的淋巴因子和单核因子的刺激作用。
B cells are activated by antigens or anti-Ig antibodies and other substances proliferation and differentiation into a large number of antibody-secreting plasma cells. This is the only source of antibody in the body. This shows that B cells occupy an important position in the humoral immune response. Therefore, the functional status of B cells and its regulatory factors very much medical attention. The activation of B cells is a continuous and complex process regulated by many factors. The most important direct effect is the stimulation of lymphokines and monokines produced by T cells and macrophages.