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目的探讨术前后MRS在胶质瘤手术切除程度评估的应用价值。方法对16例胶质瘤患者术前术后行常规MRI和3D多体素MRS检查,计算术前后的Cho/Cr和Cho/NAA的比值,寻找相等或相近的Cho/Cr和Cho/NAA比值,结合体素所在层面的位置,建立对应关系,从而评价术后切除到达范围。同时术中收集“瘤周组织”作病理检查,评估切除程度,与3D多体素MRS评估结果相比较。结果16例病人收集到完整的影像学和病理学资料有11例,病理评估为3例全切除,8例为大部分切除;3D多体素MRS评估为2例全切除,9例为大部分切除,评估结果与术后病理评估结果无显著性差异(P>0.05)。结论无创性评估胶质瘤切除程度是MRS的一项新应用,具有良好的发展前景。
Objective To investigate the value of MRS in evaluating the degree of resection of glioma before and after operation. Methods Sixteen patients with glioma underwent preoperative and postoperative routine MRI and 3D multi-voxel MRS examinations. Cho / Cr and Cho / NAA ratios were calculated before and after surgery to find equal or similar Cho / Cr and Cho / NAA Ratio, combined with the location of voxel level, the establishment of correspondence between the evaluation of postoperative resection reach. At the same time collecting “peritumoral tissue” for pathological examination to assess the degree of resection, compared with the 3D multi-voxel MRS assessment results. Results The complete imaging and pathology data of 16 patients were collected in 11 cases. Pathologic evaluation was performed in 3 cases and excision in 8 cases. 3D multi-voxel MRS was performed in 2 cases and in 9 cases Excision, assessment results and pathological evaluation results no significant difference (P> 0.05). Conclusion Noninvasive evaluation of the degree of resection of glioma is a new application of MRS, with good prospects for development.