AIM:To evaluate the clinicopathologic characteristics of the children with solitary rectal ulcer.METHODS:Fifty-five children with a confirmed diagnosis of solitary rectal ulcer were studied in a period of11 years from March 2003 to March 2014.All data were collected from the patients,their parents and medical records in the hospital.RESULTS:From 55 studied patients,41 were male(74.5%) and 14 female(25.5%).The mean age of the patients was 10.4 ± 3.7 years and the average time period from the beginning of symptoms to diagnosis of solitary rectal ulcer was 15.5 ± 11.2 mo.The most common clinical symptoms in our patients were rectal bleeding(n=54,98.2%) and straining during defecation or forceful defecation(n = 50,90.9%).Other symptoms were as follows respectively:Sense of incomplete evacuation(n = 34,61.8%),mucorrhea(n=29,52.7%),constipation(n=14,25.4%),tenesmus and cramping(n =10,18.2%),diarrhea(n= 9,16.4%),and rectal pain(n= 5,9.1%).The colonoscopic examination revealed 67.3%ulcer,12.7%polypoid lesions,10.9%erythema,7.3%both polypoid lesions and ulcer,and 1.8%normal.Most of the lesions were in the rectosigmoid area at a distance of 4-6 cm from the anal margin.Finally,69.8%of the patients recovered successfully with conservative,medical and surgical management.CONCLUSION:The study revealed that solitary rectal ulcer is not so uncommon despite what was seen in previous studies.As the most common symptom was rectal bleeding,clinicians and pathologists should be familiar with this disorder and common symptoms in order to prevent its complications with early diagnosis. AIM: To evaluate the clinicopathologic characteristics of the children with solitary rectal ulcer. METHODS: Fifty-five children with a confirmed diagnosis of solitary rectal ulcer were studied in a period of 11 years from March 2003 to March 2014. All data were collected from the patients , their parents and medical records in the hospital. RESULTS: From 55 studied patients, 41 were male (74.5%) and 14 female (25.5%). The mean age of the patients was 10.4 ± 3.7 years and the average time period from the beginning of symptoms to diagnosis of solitary rectal ulcer was 15.5 ± 11.2 mo. the most common clinical symptoms in our patients were rectal bleeding (n = 54,98.2%) and straining during defecation or forceful defecation (n = 50,90.9%). Sense of incomplete evacuation (n = 34,61.8%), mucorrhea (n = 29,52.7%), constipation (n = 14,25.4%), tenesmus and cramping (n = 10,18.2% ), diarrhea (n = 9, 16.4%), and rectal pain (n = 5, 9.1%). The colonoscopic examination revealed 67.3% ulcer, 12. 7% polypoid lesions, 10.9% erythema, 7.3% both polypoid lesions and ulcer, and 1.8% normal. Mortost of the lesions were in the rectosigmoid area at a distance of 4-6 cm from the anal margin. Fundually, 69.8% of the patients recovered successfully with conservative, medical and surgical management. CONCLUSION: The study revealed that solitary rectal ulcer is not so uncommon despite what was was in previous studies. As the most common symptom was rectal bleeding, clinicians and pathologists should be familiar with this disorder and common symptoms in order to prevent its complications with early diagnosis.