论文部分内容阅读
目的评价抗生素联合糖皮质激素治疗中老年慢性阻塞性肺气肿的疗效。方法选取2011年7月至2013年6月在我院就诊的120例慢性阻塞性肺气肿患者,采用随机方法将其分为两组,对照组给予吸氧、解痉平喘等常规治疗+抗生素,观察组在对照组基础上加用糖皮质激素。比较两组患者的治疗效果、血流动力学、肺功能及血气分析的变化情况。结果观察组总有效率明显高于对照组,无效率显著低于对照组(P<0.05)。观察组治疗后肺功能各项指标较治疗前明显升高(P<0.05),观察组治疗后肺功能各项指标均明显高于对照组(P<0.05)。观察组血气参数较治疗前及对照组均显著改善(P<0.05)。结论采用抗生素联合糖皮质激素治疗慢性阻塞性肺气肿临床疗效显著,能有效减轻患者的低氧症状,改善肺功能,值得临床借鉴使用。
Objective To evaluate the efficacy of antibiotics combined with glucocorticoid in the treatment of middle-aged and elderly patients with chronic obstructive pulmonary emphysema. Methods A total of 120 chronic obstructive pulmonary emphysema patients treated in our hospital from July 2011 to June 2013 were randomly divided into two groups. The control group was given conventional therapy such as oxygen inhalation, antispasmodic and antiasthmatic drugs plus antibiotics, The observation group was given glucocorticoid on the basis of the control group. The therapeutic effects, hemodynamics, pulmonary function and blood gas analysis were compared between the two groups. Results The total effective rate in observation group was significantly higher than that in control group, and the inefficiency rate was significantly lower than that in control group (P <0.05). The indexes of pulmonary function in observation group were significantly higher than those before treatment (P <0.05). The indexes of pulmonary function in observation group were significantly higher than those in control group (P <0.05). Blood gas parameters in the observation group were significantly improved compared with those before treatment and in the control group (P <0.05). Conclusion The combination of antibiotics and glucocorticoids in the treatment of chronic obstructive pulmonary emphysema has significant clinical curative effect, which can effectively reduce the symptoms of hypoxemia and improve pulmonary function in patients. It is worthy of clinical reference.