疟疾控制方案需要监测药物敏感性以保持最适治疗和预防措施,也有助于预防耐药疟疾的发生及传播。为了进行大规模的研究,必须有一种快速方法来检测疟原虫的氯喹敏感性。由于聚合酶链反应(PCR)对标本要求不严格,所以适用于大规模研究。 氯喹从疟原虫消化泡中快速流出是由第7条染色体上一个位点控制的。其中cg2这 Malaria control programs need to monitor drug sensitivity to maintain optimal treatment and prevention and to prevent the emergence and spread of drug-resistant malaria. For a large-scale study, there must be a quick way to test chloroquine sensitivity of the parasite. As PCR (polymerase chain reaction) is not critical to specimens, it is suitable for large-scale studies. The rapid exit of chloroquine from the digestive bulb of Plasmodium is controlled by a site on chromosome 7. Which cg2 this