迷走神经对支气管平滑肌张力的调节具有重要作用,随着人们对这一问题的逐渐认识,抗胆碱能药物用于气道解痉的临床价值又获得了重新肯定。溴化异丙托品(Ipratropiumbromide,商品名Atrovent,以下简称异丙托品)系阿托品的季胺盐衍生物,是七十年代中期开发合成的新型支气管解痉剂,近年在国外应用日益广泛。其化学结构如下。 Vagal nerve plays an important role in the regulation of bronchial smooth muscle tone. With the gradual understanding of this issue, the clinical value of anticholinergic drugs for airway spasm has been re-affirmed. Ipratropiumbromide (Ipratropiumbromide, trade name Atrovent, hereinafter referred to as Ipratropin) is a quaternary ammonium salt derivatives of atropine, is the development of the mid-seventies new synthetic bronchial spasmolytic agent, in recent years increasingly widely used in foreign countries. Its chemical structure is as follows.