动脉粥样硬化是血管壁的炎症性疾病。C反应蛋白(CRP)作为急性时相反应蛋白,不仅是一个非特异性炎症标志物,它还能影响血管平滑肌细胞的迁移和增生,参与动脉粥样硬化的发生、发展过程。血管紧张素Ⅱ作为肾素血管紧张素系统(RAS)最重要的成分是一个致炎细胞因子,可活化血管平滑肌细胞并诱导多种炎性细胞因子的释放,因此CRP和RAS之间可能存在相关性。 Atherosclerosis is an inflammatory disease of the blood vessel wall. As an acute phase reaction protein, C-reactive protein (CRP) is not only a nonspecific inflammatory marker, but also affects the migration and proliferation of vascular smooth muscle cells and plays an important role in the development and progression of atherosclerosis. As the most important component of the renin-angiotensin system (RAS), angiotensin II is a proinflammatory cytokine that activates vascular smooth muscle cells and induces the release of a variety of inflammatory cytokines and therefore there may be a correlation between CRP and RAS Sex.