论文部分内容阅读
患者:女,21岁。患者于1973年(5岁时)发现右臀部起黄豆大结节样肿块.无自觉症状。其母用针刺破后肿块开始扩大,其周围有同类皮疹出现,互相融合,逐渐增大到手掌大,时有红肿糜烂渗液。经用青霉素、链霉索治疗,感染控制。第2年春天,暗红色斑块又有扩大,上有结节渗液和痂皮。边缘清楚高起,皮疹逐渐增大至右侧全臀部、阴部、肛门周围等。外用克霉唑软膏、药水等不能控制病情发展。1982年8月以念珠菌性肉芽肿收入河南省人民医院皮肤科住院治疗3个月。多次取脓液涂片均发现大量真菌孢子,真菌培养:有白色念珠菌生长,病理检查:有乳头瘤样增生,角化过度,真皮内可见淋巴样,嗜中性、浆细胞浸润。给予克霉唑,10%碘化钾,5—氟尿嘧啶口服,二性霉素 B 静脉点滴,局部用热疗法,冷冻等治疗。皮疹基本消失,但基底部仍潮红发硬。刮片镜检
Patient: Female, 21 years old. Patients in 1973 (5 years old) found that the right hip from the large nodular tubercle mass. No symptoms. The mother began to expand after the needle acne lumps, there are similar rash around them, merging with each other, and gradually increased to the palm of your hand, sometimes red and swollen erosion exudate. With penicillin, streptomycin treatment, infection control. The first two years of spring, dark red patches have expanded, there are nodular exudate and crusts. The edge of the clear rise, the rash gradually increased to the right side of the hips, pussy, anus and so on. Topical clotrimazole ointment, syrup, etc. can not control the progression of the disease. August 1982 with Candida granuloma income Henan Provincial People’s Hospital dermatology hospital for 3 months. Multiple pus smears were found in a large number of fungal spores, fungal culture: Candida albicans growth, pathological examination: a papilloma-like hyperplasia, hyperkeratosis, dermis can be seen in lymphoid, neutrophilic, plasma cell infiltration. To give clotrimazole, 10% potassium iodide, 5-fluorouracil oral, amphotericin B intravenous drip, topical heat therapy, freezing and other treatment. The rash disappeared, but the base of the Ministry is still red and hard hair. Squeegee microscopy