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目的:探讨原发性鼻咽结核的临床特点及诊疗方法。方法:报道在我院就诊的1例以持续性耳闷胀感为首发症状的原发性鼻咽结核病例,并对相关文献进行回顾。结果:患者经鼻咽部活检、组织病理学检查,提示结核性肉芽肿伴干酪样坏死,抗酸检测阳性。经抗结核治疗后,患者症状消失,鼻咽部形态基本正常。结论:对于伴有耳部症状的鼻咽部新生物的患者,原发性鼻咽结核应作为鉴别诊断之一,须通过鼻咽部活检组织病理学检测加以明确诊断,以免延误病情。
Objective: To investigate the clinical features and diagnosis and treatment of primary nasopharyngeal tuberculosis. Methods: One case of primary nasopharyngeal tuberculosis with persistent ear discomfort as the first symptom was reported in our hospital. The related literatures were reviewed. Results: The patients were nasopharyngeal biopsy, histopathological examination, suggesting tuberculous granuloma with caseous necrosis, positive acid test. After anti-TB treatment, the patient’s symptoms disappeared, nasopharyngeal morphology was normal. Conclusion: For patients with nasopharyngeal neoplasm associated with ear symptoms, primary nasopharyngeal tuberculosis should be one of the differential diagnoses and must be diagnosed by histopathological examination of nasopharyngeal biopsies to avoid delay in disease progression.