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儿童结核病流行广泛,发病率、死亡率居高不下,WHO报道2016年全世界儿童结核病发病例数达到100万,死亡人数达到14万.为了控制儿童结核病的流行,WHO从战略上提出了“儿童结核病零死亡”的蓝图.但是儿童结核病缺乏典型症状,病变部位标本获取困难,结核分枝杆菌检出率低,儿童结核病诊断十分困难,零死亡率目前依然是巨大挑战.探寻最佳诊断方法,提高儿童结核病的早期诊断率十分必要,作者就儿童结核病的最新诊断技术做一系统性综述.“,”Childhood tuberculosis is widespread,the morbidity and mortality are both high. WHO reported that the number of childhood tuberculosis have reached to 1 million all over the world,and the number of deaths have reached 140 thousand in 2016. In order to control the prevalence of childhood tuberculosis, WHO put forward a blueprint of “ towards zero death for childhood tuberculosis”.. However,childhood tuberculosis is without typical symptoms,and it is difficult to obtain specimens. Furthermore, the bacterial rate of Mycobacterium tuberculosis is low and diagnose of childhood tuberculosis is still very difficult. Therefore, zero death is still a huge challenge. It is very necessary to detect the best diagnostic method and improve the early diagnosis rate of chiidhood tuberculosis. This review is just of the latest diagnostic technology and procedures of childhood tuberculosis.