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在以前的报道中,作者曾指出在无并发症的心肌梗塞,起病4小时内静脉注射和口服心得安,其血清肌酸激酶水平较对照组低。作者并发现在“先兆”梗塞病人,胸痛开始4小时内静脉注射或口服心得安者较少在心电图上表现为完整的梗塞。本文旨在进一步肯定梗塞开始后四小时内应用心得安能使酶水平降低,观察酶水平降低是否伴有左室收缩功能改善,以及心得安挽救梗塞前心肌是否会使之呈慢
In previous reports, the authors have pointed out that in the absence of complications of myocardial infarction, intravenous and oral propranone within 4 hours of onset, the serum creatine kinase levels lower than the control group. The authors also found that in patients with “threatened” infarctions, intravenous or oral prophylaxis within 4 hours of onset of chest pain is less likely to be a complete infarction on the electrocardiogram. This article aims to further confirm the application of propranolol within four hours after the onset of infarction to lower the level of the enzyme and to observe whether the decrease in enzyme level is associated with an improvement in left ventricular systolic function and whether or not propofol can rescue the myocardium before infarction