溶血、转氨酶水平升高和血小板计数降低的产后综合征出现致死性脑桥出血

来源 :世界核心医学期刊文摘(神经病学分册) | 被引量 : 0次 | 上传用户:liyyng1987
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Background: HELLP syndrome (a combination of hemolysis, elevated liver enzyme levels, and low platelet count) is a severe variant of preeclampsia that generally occurs before delivery but can occur post partum. This syndrome is more common than eclampsia and frequently leads to devastating neurological consequences such as intracerebral hemorrhage. Objective: Although mentioned in the obstetric literature, there has been sparse reporting in the neurology literature specifically regarding intracerebral hemorrhage in HELLP syndrome. We illustrate such a case and review the existing literature regarding this severe complication. Setting: Obstetric unit at an academic medical center. Patient: A 34-year-old primigravida experienced a pontine hemorrhage and subsequent respiratory arrest 22 hours after a normal delivery. This hemorrhage occurred 7 hours after the sudden onset of hypertension, severe headache, and intermittent abdominal pain. Results: Laboratory and postmortem evidence suggested HELLP syndrome with disseminated intravascular coagulation as the cause of her intracerebral hemorrhage. Conclusions: Our case suggests the importance of the neurology consultant’s familiarity with HELLP syndrome and the need for thorough laboratory testing and close monitoring in the puerperal patient with headache and hypertension. Background: HELLP syndrome (a combination of hemolysis, elevated liver enzyme levels, and low platelet count) is a severe variant of preeclampsia that generally occurs before delivery but can occur post partum. This syndrome is more common than eclampsia and frequently leads to devastating neurological Objective: Although mentioned in the obstetric literature, there has been been sparse reporting in the neurology literatureggle concerning intracerebral hemorrhage in HELLP syndrome. We illustrate this case and review the existing literature regard this severe complication. unit at an academic medical center. Patient: A 34-year-old primigravida experienced a pontine hemorrhage and subsequent respiratory arrest 22 hours after a normal delivery. This hemorrhage occurred 7 hours after the sudden onset of hypertension, severe headache, and intermittent abdominal pain Results: Laboratory and postmortem evidence suggest ed HELLP syndrome with disseminated intravascular coagulation as the cause of her intracerebral hemorrhage. Conclusions: Our case suggests the importance of the importance of the neurology consultant’s familiarity with HELLP syndrome and the need for thorough laboratory testing and close monitoring in the puerperal patient with headache and hypertension.
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