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目的 进一步研究缺氧时豚鼠听觉电生理的改变。 方法 观察了在不同程度的急性缺氧条件下，豚鼠听性脑干反应（ABR）的改变，结果 轻度缺氧时，ABR的阈值没有改变，但其Ⅰ波潜伏期及Ⅰ～Ⅳ间期均有延长；严重缺氧时，ABR阈值升高，Ⅰ波潜伏期进一步延长，但Ⅰ～Ⅳ间期却无进一步变化，结论 提示听觉传导通路的外周部分与中枢部分对血氧浓度变化的敏感程度存在差异，同时，ABR的阈值与潜伏期对缺氧的敏感程度也存在差异，
Objective To further investigate the electrophysiological changes in guinea pigs during hypoxia. Methods The changes of auditory brainstem response (ABR) in guinea pigs under different degrees of acute hypoxia were observed. The results showed that the threshold of ABR did not change in mild hypoxia. However, the latency of Ⅰ wave and the average of Ⅰ ~ Ⅳ interval The threshold of ABR increased and the latency of Ⅰ wave further prolonged in the condition of severe hypoxia. However, there was no further change in the interphase Ⅰ ~ Ⅳ, which suggested that the sensitivity of the peripheral part and the central part of the auditory conduction pathway to the change of the blood oxygen concentration existed Difference, at the same time, the threshold of ABR and latency are also different from the sensitivity of hypoxia,