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目的:分析乳腺癌根治术中全凭静脉麻醉的临床效果及应用体会。方法:回顾性分析120择期行乳腺癌根治术患者的临床资料,将其按照随机、对照、双盲的原则分为观察组与对照组,每组各60例,其中对照组采用吸入麻醉,观察组采用全凭静脉麻醉,比较两组患者的药物起效时间、视觉模拟量表(VAS)评分及不良反应情况。结果:观察组患进的药物起效时间显著优于对照组(P<0.05),且观察组麻醉后各时间段的VAS评分结果也显著优于对照组(P<0.05)。观察组术后出现哭闹、烦躁患者各2例,过度镇静3例,合计7例,观察组不良反应率为11.67%;对照组术后出现哭闹者5例,烦躁者6例,恶心2例,合计10例,对照组不良反应率为21.67%,对照组不良反应率显著高于观察组(P<0.05)。结论:针对行乳腺癌根治术的患者采用全凭静脉麻醉具有麻醉效果好、不良反应少的优点,具有较高的临床应用价值。
Objective: To analyze the clinical effect and application of total intravenous anesthesia in radical mastectomy of breast cancer. Methods: The clinical data of 120 patients undergoing elective radical mastectomy were retrospectively analyzed. They were divided into observation group and control group according to the principles of randomized, controlled and double-blind, with 60 cases in each group. The control group received inhalation anesthesia and observed Group using total intravenous anesthesia, the two groups of patients compared the onset time, visual analog scale (VAS) score and adverse reactions. Results: The onset time of the drugs in the observation group was significantly better than that of the control group (P <0.05). The VAS score of the observation group was also significantly better than that of the control group at each time point after anesthesia (P <0.05). In the observation group, there were 2 cases of crying and irritability, 3 cases of excessive sedation, 7 cases in total, and 11.67% of the adverse reactions in the observation group. In the control group, 5 cases of crying, 6 cases of irritability, nausea 2 Cases, a total of 10 cases, the adverse reaction rate was 21.67% in the control group, the adverse reaction rate was significantly higher in the control group (P <0.05). Conclusion: It is of high clinical value to use total intravenous anesthesia for patients undergoing radical mastectomy with good anesthetic effect and less adverse reactions.