Based on the single sensor Kalman filtering equations, this paper presents two-level and three-level optimal centralized and distributed estimation algorithms for hierarchical multisensor systems. The solution shows that when the correlated matrix, the mean of noise, the control input, and the measurement error are all zero, the result in this paper turns out to be the standard algorithm discussed. Simulation shows that the mean of noise, the control input, and the measurement error will not change the estimation covariance and the estimation covariance fluctuates greatly when the cross-correlated matrix is similar to the covariance of process noise. Based on the single sensor Kalman filtering equations, this paper presents two-level and three-level optimal centralized and distributed estimation algorithms for hierarchical multisensor systems. The solution shows that when the correlated matrix, the mean of noise, the control input, and the measurement errors are all zero, the result in this paper turns out to be the standard algorithm discussed. Simulation shows that the mean of noise, the control input, and the measurement error will not change the estimation covariance and the estimation covariance fluctuations greatly greatly the cross-correlated matrix is ​​similar to the covariance of process noise.