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目的探讨锁骨上淋巴结转移乳腺癌的综合治疗效果。方法共收治21例患者,其中9例为同期乳腺癌伴锁骨上淋巴结转移,12例为乳腺癌术后锁骨上转移。均给予新辅助化疗+手术+术后放疗、化疗或/和内分泌治疗。结果21例患者Ⅴ区淋巴结均阳性,且大部分位于颈后三角区。随访2~4年,均无颈部局部复发,4例一年半死于肺、肝及骨转移,余健在。结论结合新辅助化疗最大限度的切除原发灶及腋窝和锁骨上淋巴结等综合治疗,对改善患者的预后具有积极的作用。
Objective To investigate the comprehensive effect of supraclavicular lymph node metastasis on breast cancer. Methods A total of 21 patients were treated, including 9 cases of breast cancer with supraclavicular lymph node metastasis in the same period and 12 cases of supraclavicular metastasis after breast cancer surgery. Neonadjuvant chemotherapy + surgery + postoperative radiotherapy, chemotherapy or / and endocrine therapy were given. Results All of the 21 patients had positive lymph nodes in region Ⅴ, and most of them were located in the posterior triangle of the neck. All cases were followed up for 2 to 4 years. No local neck recurrence occurred. Four cases died of lung, liver and bone metastasis in one year and a half. Conclusion The combination of neoadjuvant chemotherapy to maximize the excision of the primary tumor and axillary and supraclavicular lymph nodes and other comprehensive treatment, to improve the prognosis of patients has a positive effect.