确实证据表明,哮喘患者呼吸道过强反应总是伴以呼吸道上皮和粘膜下层的剧烈炎性反应。 作用于气管平滑肌的内生性致痉性调协剂对哮喘呼吸道的影响大于对正常呼吸道的影响。 组织胺——这种支气管活性和血管活性调协剂,在自然发生的哮喘或由应原诱发的哮喘都被释放。很清楚,肥大细胞是作为哮喘反应的一部分而被致活的。根据诱发试验 There is indeed evidence that an overly strong respiratory response in asthmatics is always accompanied by a violent inflammatory response of the respiratory epithelium and submucosa. The effect of endogenous spasmodic agents on the smooth muscle of the trachea on the respiratory tract of asthma is greater than on the normal respiratory tract. Histamine - This bronchial and vasoactive adjuvant, is released in either naturally occurring or allergen-induced asthma. Clearly, mast cells are activated as part of an asthma response. According to induction test