羊水细胞的分子遗传学和细胞遗传学分析仍是遗传性疾病和染色体畸形产前诊断的重要组成部分。于孕16周行羊膜腔穿刺术,做聚合酶链反应(PCR)是产前遗传学诊断的新技术。由于母血可污染羊水,直接羊水污染的程度较高,细胞培养能减少污染,因此就涉及到敏感的PCR技术的应用。 孕龄14～18周妇女 53例,取约3 ml羊 Molecular and cytogenetic analysis of amniotic fluid cells remains an important part of prenatal diagnosis of genetic and chromosomal abnormalities. Amniocentesis 16 weeks pregnant, doing polymerase chain reaction (PCR) is a new technology of prenatal genetic diagnosis. As maternal blood can contaminate the amniotic fluid, amniotic fluid directly higher levels of pollution, cell culture can reduce pollution, it involves the application of sensitive PCR technology. 53 women of gestational age 14 to 18 weeks, take about 3 ml of sheep