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目的:探讨婴儿颅内出血合并低钠血症的原因及干预方法。方法:回顾性分析25例颅内出血合并低钠血症婴儿的临床资料。结果:患儿均表现为血钠下降、尿钠升高、尿比重升高、血浆平均渗透浓度下降。其中19例伴低血容量,在综合治疗基础上予输液、补钠治疗;6例无低血容量表现,予限制液体入量治疗。治疗1～3日血钠恢复正常,治疗1～2周治愈7例,好转18例。结论:婴儿颅内出血合并低钠血症为脑性耗盐综合征或抗利尿激素分泌异常综合征所致,治疗应针对病因。
Objective: To investigate the causes of infant intracranial hemorrhage with hyponatremia and intervention methods. Methods: The clinical data of 25 infants with intracranial hemorrhage and hyponatremia were retrospectively analyzed. Results: All the children presented with decreased serum sodium, elevated urinary sodium, elevated urinary specific gravity, and decreased plasma mean osmotic concentration. 19 cases with hypovolemia, on the basis of comprehensive treatment infusion, sodium supplementation; 6 cases without the performance of low blood volume, to limit the amount of fluid treatment. Serum sodium returned to normal after treatment for 1 to 3 days, 7 cases were cured in 1 to 2 weeks and 18 cases improved. Conclusion: Infant intracranial hemorrhage with hyponatremia is caused by brain salt-consuming syndrome or abnormal secretion of anti-diuretic hormone syndrome. The treatment should be aimed at the cause.