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[目的]观察热毒宁注射液联合西药治疗小儿毛细支气管炎疗效。[方法]使用随机平行对照方法,将180例住院患者按随机数字表法分为两组。对照组90例常规西药治疗,抗生素、抗病毒、吸氧、吸痰、平喘(气动雾化,严重加氨茶碱3mg/kg.d)、降温等。治疗组90例热毒宁注射液,以5%葡萄糖或0.9%氯化钠50~100mL稀释;按患儿体重0.5~0.8mL/Kg,最高剂量不超过10mL/d;静滴,15~30滴/min,1次/d。西药治疗同对照组。连续治疗7d为1疗程。观测临床症状、症状体征消失时间及住院时间、不良反应。连续治疗1疗程,判定疗效。[结果]治疗组显效51例,有效35例,无效4例,总有效率95.55%。对照组显效28例,有效44例,无效18例,总有效率80.25%。治疗组疗效优于对照组(P<0.05)。症状、体征消失时间及住院时间改善治疗组优于对照组(P<0.05)。[结论]热毒宁注射液联合常规西药治疗小儿毛细支气管炎效果显著,值得推广。
[Objective] To observe the therapeutic effect of Renduining injection combined with western medicine on bronchiolitis in children. [Methods] Using randomized parallel method, 180 inpatients were divided into two groups according to random number table method. The control group of 90 cases of conventional Western medicine, antibiotics, antiviral, oxygen, suction sputum, asthma (aerosolized, severe plus aminophylline 3mg / kg.d), cooling and so on. The treatment group, 90 cases of Rendunning injection, with 5% glucose or 0.9% sodium chloride 50 ~ 100mL diluted; children with body weight 0.5 ~ 0.8mL / Kg, the maximum dose does not exceed 10mL / d; intravenous infusion, 15 ~ 30 Drops / min, 1 time / d. Western medicine treatment with the control group. Continuous treatment 7d for a course of treatment. Observation of clinical symptoms, symptoms and signs of disappearance of time and hospital stay, adverse reactions. Continuous treatment of a course of treatment to determine the efficacy. [Results] The treatment group markedly effective in 51 cases, effective in 35 cases, 4 cases, the total effective rate was 95.55%. In the control group, 28 cases were markedly effective, 44 cases were effective, 18 cases were ineffective, and the total effective rate was 80.25%. The treatment group was better than the control group (P <0.05). Symptoms, signs of disappearance of time and hospital stay improved treatment group than the control group (P <0.05). [Conclusion] Revedun injection combined with conventional western medicine is effective in treating children with bronchiolitis and is worth promoting.