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用高效液相色谱法测定免眼房水中氟康唑的浓度，来研究月桂氮酮对氟康唑角膜渗透性的影响。结果表明：用含0．02％，0．04％，0．08％和0．10％月桂氮酮的氟康唑滴眼液滴眼，能使兔眼房水中氟康唑的浓度分别增加2．5、3．5、4．0和4．2倍。提示月桂氮酮可提高氟康唑的疗效。
The effect of Azone on the corneal permeation of fluconazole was studied by high performance liquid chromatography for the determination of fluconazole in non-aqueous humor. The results showed that the fluconazole concentration in aqueous humor of rabbits increased respectively with Fluconazole Eye Drops containing 0.02%, 0.04%, 0.08% and 0.10% Azone 2.5, 3.5, 4.0 and 4.2 times. Tip Azone Azone can improve the efficacy of fluconazole.