本文报道了小鼠全肺受X线照射后早期可在肺泡中测出明显增高的表面活性物质,且在8～17Gy剂量范围内,肺泡表面活性物质含量的增高与照射剂量有一定线性关系。应用中药活血化瘀制剂764-1可明显降低肺照射后肺泡内表面活性物质的增高,而对正常肺泡内表面活性物质水平无影响,提示764-1对肺Ⅱ型细胞这种放射损伤效应有较好的改善作用。至于这种改善作用机理有待进一步探讨。 In this paper, we report that in the early stage of the whole lung exposure to X-ray, the surface active substances detected in the alveoli are significantly increased. The increase of alveolar surfactant content in the dose range of 8 ~ 17Gy has a certain linear relationship with the irradiation dose. Application of Chinese medicine promoting blood circulation and removing blood stasis preparation 764-1 can significantly reduce the lung alveolar surface active substances increased, but no effect on the normal alveolar surface activity of the substance, suggesting that 764-1 of lung Ⅱ type of cell radiation damage effect Better to improve the role. As for this mechanism to improve the role to be further explored.