论文部分内容阅读
目的:了解2007~2011年吉林省出生缺陷的流行特征,为探讨降低本省出生缺陷干预措施提供科学依据。方法:按照国家出生缺陷监测方案,对2007~2011年吉林省监测医院出生的孕28周至生后7天所有围产儿进行出生缺陷监测。结果:5年间吉林省共监测围产儿913 998例,发现缺陷儿7 967例,出生缺陷总发生率为87.17/万,前5位缺陷类型依次为:先天性心脏病、总唇裂、多指(趾)、先天性脑积水和神经管缺陷。农村和城镇地区的出生缺陷发生率分别为76.12/万和101.35/万。男性和女性围产儿的出生缺陷发生率分别为94.37/万和77.50/万。结论:吉林省神经管缺陷发生率降低明显,先天性心脏病发生率和在5岁以下儿童死因顺位升高明显。应积极实施预防出生缺陷措施,提高本地区产前筛查及产前诊断能力,降低出生缺陷发生水平,提高出生人口素质。
Objective: To understand the epidemiological characteristics of birth defects in Jilin Province from 2007 to 2011, and to provide a scientific basis for exploring intervention measures to reduce the birth defects in this province. Methods: According to the monitoring program of birth defects in our country, we monitored the birth defects of all perinatals born in Jilin Provincial Monitoring Hospital from 2007 to 2011 from 28 weeks to 7 days after birth. Results: A total of 913 998 perinatal infants were detected in Jilin Province during the five years. A total of 7 967 infants were found defective. The total incidence of birth defects was 87.17 / 000. The top five defect types were congenital heart disease, total cleft lip, multiple fingers Toe), congenital hydrocephalus and neural tube defects. The incidence of birth defects in rural and urban areas was 76.12 / million and 101.35 / million, respectively. The incidence of birth defects in both men and women was 94.37 / million and 77.50 / million, respectively. Conclusion: The incidence of neural tube defects in Jilin Province decreased obviously. The incidence of congenital heart disease and the cause of death in children under 5 years old increased significantly. Measures to prevent birth defects should be actively implemented to improve prenatal screening and prenatal diagnosis in this area, to reduce the incidence of birth defects and to improve the quality of the birth population.