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目的观察阿奇霉素治疗社区小儿支原体肺炎的临床效果。方法选择社区收治的小儿支原体肺炎患儿80例为研究对象,随机分为常规组和阿奇霉素组,每组40例。常规组给予常规治疗,阿奇霉素组在常规治疗基础上增加阿奇霉素治疗。比较2组患儿支原体肺炎控制有效率;发热、气促、咳嗽、肺部哮鸣音持续时间;用药前和用药2周患儿CRP、FVC、FEV1的差异。结果阿奇霉素组治疗总有效率为92.50%,显著高于常规组的75.00%(P<0.01);用药2周,阿奇霉素组CRP、FVC、FEV1数值较常规组改善明显(P<0.05);阿奇霉素组发热、气促、咳嗽、肺部哮鸣音持续时间均短于常规组(P<0.01)。结论阿奇霉素治疗社区小儿支原体肺炎的临床疗效确切,可有效改善患儿临床症状,促进症状消退,减轻机体炎性反应水平,改善患儿肺功能,值得推广应用。
Objective To observe the clinical effect of azithromycin in treating children with mycoplasma pneumonia in community. Methods Eighty children with pediatric mycoplasma pneumonia admitted to the community were enrolled in this study. They were randomly divided into routine and azithromycin groups, 40 in each. The conventional group was given conventional treatment, and the azithromycin group was treated with azithromycin on the basis of conventional treatment. Comparison of two groups of children with mycoplasma pneumonia control efficiency; fever, shortness of breath, cough, lung wheeze duration; before treatment and medication for 2 weeks in children with CRP, FVC, FEV1 differences. Results The total effective rate of azithromycin group was 92.50%, which was significantly higher than that of the conventional group (P <0.01). The CRP, FVC and FEV1 values of the azithromycin group were significantly improved (P <0.05) Fever, shortness of breath, cough, lung wheeze duration were shorter than the conventional group (P <0.01). Conclusion Azithromycin treatment of community children with mycoplasma pneumonia clinical curative effect is exact, can effectively improve children’s clinical symptoms, promote symptoms, reduce the level of inflammatory response in the body, improve children’s lung function, it is worth promoting the application.