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目的:观察速避凝治疗急性缺血性卒中的疗效,以寻求治疗缺血性卒中的新药物。方法;速避凝治疗组36例,以速避凝4 100u皮下注射,每12小时1次,同时给予20%甘露醇125ml静脉滴注,每日2次。对照组35例,给予20%甘露醇125ml静脉滴注,每日2次,联合应用复方丹参16ml静脉滴注每日1次。二组均以10～14天为一个疗程。评价出二组患者的疗效。结果:治疗组与对照组显效率分别为77.8%和57.1%,两组显效率相比较,差异有显著意义(P<0.01)。同时,治疗组血液流变学指标有异常改变者联合应用速避凝与甘露醇治疗后各项指标均有明显改善,治疗前后比较有极显著性差异(P<0.01)。结论:速避凝与甘露醇联用对缺血性卒中有明显疗效。
OBJECTIVE: To observe the efficacy of rapid A-coagulation in the treatment of acute ischemic stroke in order to seek new drugs for the treatment of ischemic stroke. Methods; 36 cases of rapid avoidance treatment group, 4OOu speed subcutaneous injection of contraception, once every 12 hours, while giving 20% mannitol 125ml intravenous infusion of 2 times a day. Control group of 35 patients given 20% mannitol 125ml intravenous drip twice a day, combined with compound Danshen 16ml intravenous infusion of 1 day. The two groups were 10 to 14 days for a course of treatment. Evaluation of the efficacy of two groups of patients. Results: The effective rates of the treatment group and the control group were 77.8% and 57.1%, respectively. There was significant difference between the two groups (P <0.01). At the same time, the indexes of hemorheology in the treatment group had abnormal changes. The combination of rapid avoidance coagulation and mannitol treatment significantly improved the indexes of all the indexes. There was a significant difference before and after treatment (P <0.01). Conclusion: Combination of rapid avoidance and mannitol has obvious curative effect on ischemic stroke.